Objectives: We previously found that the pluripotency factor OCT4 is reactivated in smooth muscle cells (SMC) in human and mouse atherosclerotic plaques and plays an atheroprotective role.Loss of OCT4 in SMC in vitro was associated with decreases in SMC migration.However, molecular mechanisms responsible for atheroprotective SMC-OCT4-dependent effe
Environmental enrichment is a critical component of Refinement, one of the 3Rs underlying humane experimentation on animals.In this paper I discuss why primates housed in laboratories, which often have constraints of space and study protocols, are a special case for enrichment.I outline a framework for categorising the different types of enrichment
The purpose of this study was to establish the normal renal artery parameters in German Shepherd dogs.Consequently, the acquired values can be applied to the subsequent clinical research and the interpretation of the findings.Doppler ultrasound was used in this study to assess 24 healthy German shepherd dogs, including 11 female dogs (45.8%) and AY
The works written by Dimitrie Cantemir in Latin language are meant to respond to Hunting Gloves the curiosity the author assumes that characterizes his readers.He accomplishes his purpose in a multifarious manner, mostly by offering precise data extracted from an extensive bibliography.Nonetheless, his personal experience is frequently a valuable s